RESEARCH ARTICLE
Valorization of Vegetable Waste: Identification of Bioactive Compounds and Their Chemo-Enzymatic Optimization
Carmela Spatafora, Corrado Tringali*
Article Information
Identifiers and Pagination:
Year: 2012Volume: 6
First Page: 9
Last Page: 16
Publisher ID: TOASJ-6-9
DOI: 10.2174/1874331501206010009
Article History:
Received Date: 12/11/2009Revision Received Date: 16/11/2010
Acceptance Date: 08/02/2011
Electronic publication date: 03/2/2012
Collection year: 2012
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
A growing demand – above all in industrialised countries – for safer foods and cleaner production processes has been observed in recent times. This has led to a drive, by the agro-alimentary industries, for waste reduction and upgrading as a strategy to reduce costs and achieve new sources of income. In fact, waste may be a source of high-added value products potentially useful as beneficial food constituents, food flavours and antioxidants, cosmetics, chemopreventive agents, drugs or drug adjuvants. In this regard, we have recently examined some vegetable wastes available in the Mediterranean basin as bioresources of useful compounds and we report here a short account of our work as an example of integrated approach between the query of agro-food industry for waste upgrading and the search of some sectors of chemical industry for bioactive products obtainable from renewable resources. We employed two different strategies aimed to the exploitation of vegetable by-products: 1) Identification or isolation of bioactive natural products in vegetable waste as possible source of lead compounds or enriched fractions. 2) Chemical and enzymatic modification of lead compounds available from vegetable waste to obtain optimized analogues, food additives, drugs or cosmetics. The results here summarised are focused on: a) isolation of antiproliferative constituents from almond (Prunus dulcis) hulls and grape (Vitis vinifera) stems; b) chemical analysis of extracts / fractions with antioxidant properties obtained from grape pomace and grape stems; c) chemical / enzymatic modification of hydroxytyrosol (26) and trans-resveratrol (11), two bioactive polyphenols available from vegetable waste.