Disruption of Tight Junction Integrity, and Induced Mammary Involution in Lactating Goats by Saponins
S.J. Mabjeesh*, 1, Z. Kerem2, C. Sabastian1, A. Shamay3
Identifiers and Pagination:Year: 2007
First Page: 1
Last Page: 4
Publisher Id: TOASJ-1-1
Article History:Received Date: 30/08/2007
Revision Received Date: 04/09/2007
Acceptance Date: 08/09/2007
Electronic publication date: 21/9/2007
Collection year: 2007
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Four multiparous pregnant Nubian goats at late lactation were subjected to injection of a saponin preparation from Gypsophila roots. Saponin solution was injected into one single gland of each goat after milking 8 times. At day 2 in treatment, milk yield began to be affected, and dropped down dramatically from day 3 till dry off at day 8. The pH value of milk was increased in udder halves treated with the saponin solution after 2 days, whereas the control halves exhibited semi-plateau manner all over the experiment. Sodium concentration increased and potassium concentration decreased after 2 d in treatment. Calcium concentration in the treated udder declined after 8 d and the values of these ions were roundabout the plasma concentrations indicating that milk secreted from the treated udder halves with saponins was mostly composed of interstitial fluid.